Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668769 | 0.89 | PRKAA2 (0.40) | MEN1KMT2A | |
| SCHEMBL1668252 | 0.83 | GPR119 (0.49) | ACACBMEN1KMT2AGPR119PANK3 | |
| SCHEMBL13894795 | 0.76 | MEN1 (0.43) | ACACBMEN1KMT2A | |
| SCHEMBL3661425 | 0.76 | MEN1 (0.43) | ACACBMEN1KMT2A | |
| SCHEMBL1668287 | 0.74 | GPR119 (0.46) | KMT2AGPR119 | |
| SCHEMBL1668614 | 0.73 | PRKAA2 (0.39) | — | |
| SCHEMBL1668307 | 0.72 | KDR (0.45) | ACACBMEN1KMT2AGPR119 | |
| SCHEMBL1668753 | 0.72 | GPR119 (0.46) | MEN1KMT2AGPR119 | |
| SCHEMBL1670864 | 0.72 | GPR119 (0.46) | MEN1KMT2AGPR119 | |
| SCHEMBL1668953 | 0.72 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486033-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2012-08-15 | — | — | EP | claimed |
| WO-2011044001-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-04-14 | — | — | WO | claimed |