SCHEMBL16685271

SCHEMBL16685271

Cc1cc(C)c(-c2cccnc2)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 9/20 0.54
CYP3A4 P08684 4/20 0.54
ALDH1A1 P00352 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2E1 P05181 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2B6 P20813 2/20 0.49
CYP2C19 P33261 2/20 0.49
ACLY P53396 2/20 0.48
TP53 P04637 2/20 0.48
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ALK Q9UM73 1/20 0.47
CYP17A1 P05093 2/20 0.47
CYP19A1 P11511 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28122684 0.98 CYP2A6 (0.52) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL23242620 0.98 CYP2A6 (0.52) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL28431976 0.89 ACLY (0.53) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL13785076 0.85 CYP2A6 (0.47) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL21476509 0.83 CYP2A6 (0.60) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL23096923 0.83 KIF11 (0.61) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL14327641 0.82 CYP2A6 (0.52) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL22693743 0.82 CYP2A6 (0.42) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL13785062 0.81 CYP2A6 (0.47) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1
SCHEMBL29514840 0.81 CYP2A6 (0.50) CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102903854-A White-light organic electroluminescent device and production method thereof UNIV ELECTRONIC SCIENCE & TECH 2013-01-30 CN claimed
WO-2015063543-A1 HYDRIDOPALLADIUM(II) HALIDES AS PREFORMED CATALYSTS FOR SUZUKI-MIYAURA CROSS-COUPLING REACTIONS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2015-05-07 WO disclosed
WO-2015063543-A1 HYDRIDOPALLADIUM(II) HALIDES AS PREFORMED CATALYSTS FOR SUZUKI-MIYAURA CROSS-COUPLING REACTIONS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2015-05-07 WO disclosed
CN-102903854-A White-light organic electroluminescent device and production method thereof UNIV ELECTRONIC SCIENCE & TECH 2013-01-30 CN disclosed