SCHEMBL16685293

SCHEMBL16685293

C=Cc1c(F)cccc1F.C=Cc1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
NFE2L2 Q16236 8/20 0.42
TSHR P16473 1/20 0.41
KCNH2 Q12809 2/20 0.38
MAT2A P31153 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HDAC8 Q9BY41 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193995 0.84 NFE2L2 (0.46) ALDH1A1NFE2L2TSHRKCNH2MAT2A
SCHEMBL49710 0.82
SCHEMBL12143704 0.82
Methane SCHEMBL11604289 0.79 ALDH1A1 (0.65) ALDH1A1NFE2L2TSHRTDP1HDAC8
Hydrogen Sulfide SCHEMBL29004374 0.79 ALDH1A1 (0.65) ALDH1A1NFE2L2TSHRTDP1HDAC8
SCHEMBL29026744 0.75 ALDH1A1 (0.58) ALDH1A1NFE2L2TSHRTDP1HDAC8
SCHEMBL8758686 0.75 ALDH1A1 (0.58) ALDH1A1NFE2L2TSHRTDP1HDAC8
SCHEMBL28518781 0.73 ALDH1A1 (0.55) ALDH1A1NFE2L2TSHRTDP1HDAC8
SCHEMBL11671543 0.72 ALDH1A1 (0.48) ALDH1A1NFE2L2TSHRKCNH2MAT2A
SCHEMBL15449507 0.72 ALDH1A1 (0.48) ALDH1A1NFE2L2TSHRKCNH2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3408016-B1 POLYMERIC DISPERSANTS CONTAINING MULTI-AMINE GROUPS WITH IMPROVED CHEMICAL AND THERMAL STABILITY LUBRIZOL ADVANCED MAT INC (US) 2023-11-22 EP disclosed
US-11649309-B2 Acrylic dispersants with fused aromatic imide anchor groups LUBRIZOL ADVANCED MATERIALS, INC (US) 2023-05-16 US disclosed
US-20200325264-A1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MAT INC (US) 2020-10-15 US disclosed
US-10745506-B2 Acrylic dispersants with fused aromatic imide anchor groups LUBRIZOL ADVANCED MATERIALS INC (US) 2020-08-18 US disclosed
EP-3408016-A1 POLYMERIC DISPERSANTS CONTAINING MULTI-AMINE GROUPS WITH IMPROVED CHEMICAL AND THERMAL STABILITY Lubrizol Advanced Materials, Inc. (US) 2018-12-05 EP disclosed
EP-3066166-B1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MAT INC (US) 2018-03-28 EP disclosed
WO-2017132380-A1 POLYMERIC DISPERSANTS CONTAINING MULTI-AMINE GROUPS WITH IMPROVED CHEMICAL AND THERMAL STABILITY LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-08-03 WO disclosed
EP-3066166-A1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS Lubrizol Advanced Materials, Inc. (US) 2016-09-14 EP disclosed
US-20160257774-A1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MAT INC (US) 2016-09-08 US disclosed
WO-2015066163-A1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-07 WO disclosed