Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 10/20 | 0.75 |
| ▸ | STARD10 | Q9Y365 | 5/20 | 0.75 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235186 | 0.85 | PCTP (1.00) | PCTPSTARD10STARD7LMNAGPR27 | |
| SCHEMBL1235180 | 0.83 | PCTP (1.00) | PCTPSTARD10STARD7LMNA | |
| SCHEMBL1233511 | 0.75 | PCTP (1.00) | PCTPSTARD10STARD7LMNA | |
| SCHEMBL17280988 | 0.72 | PCTP (0.75) | PCTPSTARD10STARD7LMNAGPR27 | |
| SCHEMBL9349980 | 0.71 | CYP2C19 (0.68) | PCTPSTARD10GRM4LMNAALDH1A1 | |
| SCHEMBL1235824 | 0.70 | PCTP (0.72) | PCTPSTARD10STARD7LMNAGPR27 | |
| SCHEMBL13470344 | 0.69 | PCTP (0.60) | PCTPSTARD10STARD7LMNAALDH1A1 | |
| SCHEMBL1233504 | 0.68 | PCTP (1.00) | PCTPSTARD10STARD7LMNAGPR27 | |
| SCHEMBL29556377 | 0.67 | PCTP (0.58) | PCTPSTARD10LMNAGPR27ALDH1A1 | |
| SCHEMBL28347229 | 0.67 | PCTP (0.58) | PCTPSTARD10LMNAGPR27ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065876-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2015-05-07 | — | — | WO | disclosed |