SCHEMBL28347229

SCHEMBL28347229

CNC(=O)Nc1ccc(S(=O)(=O)NC(=O)c2cccc(Cl)c2Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCTP Q9UKL6 2/20 0.58
STARD10 Q9Y365 1/20 0.58
FLT1 P17948 2/20 0.53
FLT4 P35916 2/20 0.53
KDR P35968 2/20 0.53
BDKRB1 P46663 1/20 0.50
GPR27 Q9NS67 1/20 0.48
KMT2A Q03164 3/20 0.48
FAAH O00519 1/20 0.47
MGLL Q99685 1/20 0.47
LMNA P02545 2/20 0.47
JAK2 O60674 1/20 0.47
ALDH1A1 P00352 1/20 0.46
TP53 P04637 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556377 1.00 PCTP (0.58) PCTPSTARD10FLT1FLT4KDR
SCHEMBL9483016 0.85 FLT1 (0.49) PCTPSTARD10FLT1FLT4KDR
SCHEMBL9483319 0.85 FLT1 (0.48) PCTPSTARD10FLT1FLT4KDR
SCHEMBL9468161 0.81 FLT1 (0.52) FLT1FLT4KDRBDKRB1KMT2A
SCHEMBL9484652 0.81 BDKRB1 (0.56) FLT1FLT4KDRBDKRB1KMT2A
SCHEMBL14376040 0.81 KDM4E (0.65) FLT1FLT4KDRBDKRB1KMT2A
SCHEMBL9468135 0.81 PLK1 (0.54) FLT1FLT4KDRBDKRB1KMT2A
SCHEMBL9484328 0.79 BCAT2 (0.57) FLT1FLT4KDRBDKRB1KMT2A
SCHEMBL4476646 0.78 FLT1 (0.72) PCTPFLT1FLT4KDRBDKRB1
SCHEMBL248487 0.78 RXFP1 (0.58) FLT1FLT4KDRBDKRB1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114761393-A Heteroaryl substituted pyrazine derivatives as pesticides 拜耳动物保健有限责任公司 2022-07-15 CN disclosed
CN-114423748-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2022-04-29 CN disclosed
CN-113994970-A Substituted sulfonamides for combating animal pests 拜耳公司 2022-02-01 CN disclosed
CN-113939509-A Novel heteroaryl substituted aminoalkylazole compounds as pesticides 拜耳动物保健有限责任公司 2022-01-14 CN disclosed
CN-113490663-A Pyridazine (thio) amides as fungicidal compounds 拜耳公司 2021-10-08 CN disclosed
CN-113454079-A Heterocyclylpyridazines as fungicidal compounds 拜耳公司 2021-09-28 CN disclosed
CN-112996782-A Pyridylphenylaminoquinolines and analogs 拜耳公司 2021-06-18 CN disclosed
CN-112912374-A Oxocyclobutylphenoxyquinolines and analogs 拜耳公司 2021-06-04 CN disclosed
CN-112204021-A Novel heteroaryltriazole and heteroaryltetrazole compounds as pesticides 拜耳公司 2021-01-08 CN disclosed
CN-110603253-A Heteroaryl phenylamino quinolines and analogs 拜耳公司 2019-12-20 CN disclosed