Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685760 | 1.00 | MAOA (0.40) | MAOAMAOBF10MEN1MAPT | |
| SCHEMBL16686255 | 0.86 | MAOA (0.55) | MAOAMAOBF10MEN1MAPT | |
| SCHEMBL16686258 | 0.86 | MAOA (0.55) | MAOAMAOBF10MEN1MAPT | |
| SCHEMBL16686174 | 0.85 | GRM2 (0.44) | MAOAMAOBF10GRM2 | |
| SCHEMBL16686176 | 0.85 | GRM2 (0.44) | MAOAMAOBF10GRM2 | |
| SCHEMBL28922753 | 0.80 | GRM2 (0.49) | MAOAMAOBMAPTGRM2 | |
| SCHEMBL16696395 | 0.79 | GRM2 (0.39) | MAOAMAOBF10GRM2 | |
| SCHEMBL16686237 | 0.79 | GRM2 (0.50) | F10GRM2 | |
| SCHEMBL16686236 | 0.79 | GRM2 (0.50) | F10GRM2 | |
| SCHEMBL16685839 | 0.76 | F10 (0.36) | MAOAMAOBF10GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |