Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668505 | 0.90 | OPRD1 (0.51) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL1669154 | 0.83 | OPRD1 (0.51) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL16499539 | 0.80 | OPRD1 (0.52) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL16498945 | 0.80 | OPRD1 (0.52) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL16498943 | 0.80 | OPRD1 (0.52) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL12800770 | 0.80 | OPRD1 (0.42) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL1669123 | 0.79 | OPRD1 (0.51) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL12801195 | 0.78 | KDM4E (0.42) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL16499347 | 0.78 | OPRD1 (0.50) | OPRD1OPRK1TSHRALOX15ATM | |
| SCHEMBL1950809 | 0.78 | IP6K1 (0.52) | PKMJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |