Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | CALML3 | P27482 | 6/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SDHA | P31040 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16686180 | 1.00 | MAOA (0.38) | MAOACALML3GRM2MAOBLMNA | |
| SCHEMBL16685846 | 0.86 | CALML3 (0.50) | MAOACALML3GRM2MAOB | |
| SCHEMBL16685849 | 0.86 | CALML3 (0.50) | MAOACALML3GRM2MAOB | |
| SCHEMBL16686176 | 0.82 | GRM2 (0.44) | MAOACALML3GRM2MAOBLMNA | |
| SCHEMBL16686174 | 0.82 | GRM2 (0.44) | MAOACALML3GRM2MAOBLMNA | |
| SCHEMBL16686245 | 0.77 | CALML3 (0.50) | MAOACALML3GRM2MAOBLMNA | |
| SCHEMBL16686244 | 0.77 | CALML3 (0.50) | MAOACALML3GRM2MAOBLMNA | |
| SCHEMBL16686236 | 0.75 | GRM2 (0.50) | GRM2F10 | |
| SCHEMBL16686237 | 0.75 | GRM2 (0.50) | GRM2F10 | |
| SCHEMBL8594735 | 0.75 | GRM2 (0.48) | MAOACALML3GRM2MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |