Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092627 | 0.82 | POLB (0.50) | ALDH1A1TRPV1HPGDPOLBHRH3 | |
| SCHEMBL16685886 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1LMNAHPGDPOLBSRC | |
| SCHEMBL17538445 | 0.80 | ALDH1A1 (0.61) | ALDH1A1LMNANR3C1KDM4ESMN1; SMN2 | |
| SCHEMBL2022898 | 0.79 | POLB (0.57) | ALDH1A1TRPV1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL3039450 | 0.79 | NPC1 (0.56) | ALDH1A1HPGDPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL2019464 | 0.78 | POLB (0.70) | ALDH1A1TRPV1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL16245932 | 0.78 | RAB9A (0.47) | ALDH1A1TRPV1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL114997 | 0.77 | MAPT (0.54) | ALDH1A1LMNANR3C1HPGDPOLB | |
| SCHEMBL5789 | 0.77 | CYP4F2 (0.48) | TRPV1HPGDPPARAPOLBHRH3 | |
| SCHEMBL5619 | 0.77 | POLB (0.46) | ALDH1A1TRPV1HPGDPOLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |