Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.53 |
| ▸ | CES1 | P23141 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23972274 | 0.87 | CES2 (0.66) | CES2CES1ALBGLSBCHE | |
| SCHEMBL1668559 | 0.87 | CES2 (0.66) | CES2CES1ALBGLSBCHE | |
| SCHEMBL31407017 | 0.87 | CES2 (0.66) | CES2CES1ALBGLSBCHE | |
| SCHEMBL31407025 | 0.87 | CES2 (0.66) | CES2CES1ALBGLSBCHE | |
| SCHEMBL1668558 | 0.87 | CES2 (0.66) | CES2CES1ALBGLSBCHE | |
| SCHEMBL1668625 | 0.81 | CES2 (0.46) | CES2CES1CA12CA1CA2 | |
| SCHEMBL1668624 | 0.81 | CES2 (0.46) | CES2CES1CA12CA1CA2 | |
| SCHEMBL617480 | 0.74 | CA12 (0.70) | CES2CES1CA12CA1CA2 | |
| SCHEMBL31263802 | 0.74 | CA12 (0.57) | CES2CES1CA12CA1CA2 | |
| SCHEMBL11354965 | 0.73 | CES2 (0.63) | CES2CES1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |