Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.66 |
| ▸ | CES1 | P23141 | 6/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23972274 | 1.00 | CES2 (0.66) | CES2CES1BCHEGLSLMNA | |
| SCHEMBL31407025 | 1.00 | CES2 (0.66) | CES2CES1BCHEGLSLMNA | |
| SCHEMBL1668558 | 1.00 | CES2 (0.66) | CES2CES1BCHEGLSLMNA | |
| SCHEMBL1668559 | 1.00 | CES2 (0.66) | CES2CES1BCHEGLSLMNA | |
| SCHEMBL1668623 | 0.87 | CES2 (0.53) | CES2CES1BCHEGLSLMNA | |
| SCHEMBL1671676 | 0.83 | CES2 (0.63) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL30670483 | 0.83 | CES2 (0.63) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL469655 | 0.83 | CES2 (0.63) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL11354965 | 0.83 | CES2 (0.63) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL19716935 | 0.82 | CES2 (0.64) | CES2CES1BCHEGLSALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | disclosed |