Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685985 | 0.78 | IDO1 (0.42) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16685865 | 0.78 | IDO1 (0.42) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16685993 | 0.77 | IDO1 (0.41) | NPSR1 | |
| SCHEMBL22440077 | 0.76 | HTT (0.44) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14722833 | 0.73 | FABP7 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21061656 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL6928220 | 0.73 | CDK5 (0.48) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21061655 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL26633765 | 0.73 | SMN1; SMN2 (0.64) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16685927 | 0.72 | HTT (0.45) | HTTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |