Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685865 | 0.78 | IDO1 (0.42) | IDO1AGXTNAAAFAAHMGLL | |
| SCHEMBL16685985 | 0.78 | IDO1 (0.42) | IDO1AGXTNAAAFAAHMGLL | |
| SCHEMBL16686234 | 0.77 | HTT (0.45) | NPSR1 | |
| SCHEMBL16685900 | 0.73 | NAAA (0.51) | IDO1AGXTPYCR1NAAAPDE2A | |
| SCHEMBL16685703 | 0.71 | IDO1 (0.41) | IDO1AGXTPYCR1NAAAPDE2A | |
| SCHEMBL17723908 | 0.66 | IDO1 (0.42) | IDO1AGXTAPPMAOB | |
| SCHEMBL3803477 | 0.64 | IDO1 (0.52) | IDO1AGXTPYCR1PDE2AAPP | |
| SCHEMBL22729788 | 0.64 | PYCR1 (0.61) | PYCR1CHRM2 | |
| SCHEMBL28829904 | 0.64 | GLA (0.50) | IDO1AGXTMAOBGLANPSR1 | |
| SCHEMBL21107127 | 0.64 | IDO1 (0.47) | IDO1AGXTAPPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |