SCHEMBL16686266

SCHEMBL16686266

O=C1O[C@@H](CO)CN1c1ccc2ccccc2c1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.64
MAOB P27338 1/20 0.64
CALML3 P27482 6/20 0.55
GRM2 Q14416 8/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9205426 1.00 MAOA (0.64) MAOAMAOBCALML3GRM2
SCHEMBL16686070 0.86 GRM2 (0.49) MAOAMAOBGRM2
SCHEMBL16686068 0.86 GRM2 (0.49) MAOAMAOBGRM2
SCHEMBL9211302 0.86 F10 (0.54) MAOAMAOBGRM2
SCHEMBL6269776 0.83 GRM2 (0.56) GRM2
SCHEMBL9213579 0.83 MAOB (0.47) MAOAMAOBCALML3GRM2
SCHEMBL8701781 0.82 MAOA (0.56) MAOAMAOBCALML3
SCHEMBL4638737 0.82 GRM2 (0.69) MAOAMAOBGRM2
SCHEMBL1874998 0.82 GRM2 (0.69) MAOAMAOBGRM2
SCHEMBL12635778 0.82 GRM2 (0.69) MAOAMAOBGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015066413-A1 OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS NOVARTIS AG (CH) 2015-05-07 WO disclosed