Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CALML3 | P27482 | 6/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8787732 | 0.87 | F10 (0.47) | MAOAMAOBCALML3ACACBPSMD14 | |
| SCHEMBL9029466 | 0.84 | MAOA (0.55) | MAOAMAOBCALML3ACACB | |
| Hydrochloric Acid SCHEMBL8695876 | 0.83 | MAOA (0.54) | MAOAMAOBCALML3ACACB | |
| SCHEMBL2827335 | 0.82 | GRM2 (0.62) | — | |
| SCHEMBL16686266 | 0.82 | MAOA (0.64) | MAOAMAOBCALML3 | |
| SCHEMBL9205426 | 0.82 | MAOA (0.64) | MAOAMAOBCALML3 | |
| SCHEMBL2825607 | 0.77 | GRM2 (0.65) | — | |
| SCHEMBL14183582 | 0.76 | MAOA (0.61) | MAOAMAOBCALML3CYP3A4CYP2D6 | |
| SCHEMBL8788776 | 0.76 | MAOA (0.49) | MAOAMAOBCALML3CYP2C19CYP3A4 | |
| SCHEMBL7068856 | 0.75 | GRM2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843967-A | 6-membered nitrogen-containing heteroaryl-oxazolidinones | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| EP-0785197-A2 | 2-oxo and 2-thio-1,2-dihydroquinolinyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| US-5627181-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0694543-A1 | 6-membered N-heteroaryloxazolidinones | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |