Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165 | 0.83 | NAPRT (0.45) | NAPRT | |
| Water SCHEMBL29957279 | 0.81 | NAPRT (0.44) | NAPRT | |
| Water SCHEMBL29956357 | 0.81 | NAPRT (0.44) | NAPRT | |
| Water SCHEMBL343330 | 0.81 | NAPRT (0.44) | NAPRT | |
| SCHEMBL29547429 | 0.81 | ENPP2 (0.39) | CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL8593 | 0.81 | ENPP2 (0.39) | CYP3A4CYP2A6CYP2B6CYP2C19 | |
| Hydrochloric Acid SCHEMBL18889249 | 0.79 | ENPP2 (0.37) | CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL7931541 | 0.70 | CYP2A6 (0.38) | CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL4537667 | 0.68 | NAPRT (0.39) | NAPRTMAPT | |
| SCHEMBL24092914 | 0.68 | NAPRT (0.41) | NAPRTMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |