SCHEMBL8593

SCHEMBL8593

OB(O)c1ccc(F)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 4/20 0.39
MGLL Q99685 2/20 0.38
CA2 P00918 3/20 0.37
CA1 P00915 2/20 0.37
TSHR P16473 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
CYP2A6 P11509 2/20 0.36
CYP2B6 P20813 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP2E1 P05181 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29547429 1.00 ENPP2 (0.39) ENPP2MGLLCA2CA1TSHR
Hydrochloric Acid SCHEMBL18889249 0.98 ENPP2 (0.37) ENPP2MGLLCA2CA1TSHR
SCHEMBL7931541 0.82 CYP2A6 (0.38) ORAI1ORAI2ORAI3TRPV6CYP2A6
SCHEMBL1668650 0.81 NAPRT (0.34) CYP2A6CYP2B6CYP3A4CYP2C19
SCHEMBL24444783 0.77 CYP2A6 (0.32) ORAI1ORAI2ORAI3TRPV6CYP2A6
SCHEMBL25686350 0.77 CYP2A6 (0.35) ENPP2CA2CA1ORAI1ORAI2
SCHEMBL24092776 0.76 CYP2A6 (0.36) CYP2A6CYP2B6CYP3A4CYP2C19CYP2E1
SCHEMBL38656446 0.75 ENPP2 (0.42) ENPP2MGLLCA2CA1TSHR
SCHEMBL26314552 0.75 ENPP2 (0.42) ENPP2MGLLCA2CA1TSHR
SCHEMBL519749 0.73 ENPP2 (0.46) ENPP2MGLLCA2CA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2565 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-118307565-A FHND507 and 507 synthesis method 南京师范大学 2024-07-09 CN claimed
CN-115160300-B Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2024-05-31 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
US-11737481-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-08-29 US claimed
CN-113321668-A Synthesis of serpatatinib 江苏慧聚药业有限公司 2021-08-31 CN claimed
CN-112687878-A Electrochemical device and electronic device 东莞新能源科技有限公司 2021-04-20 CN claimed
EP-2155681-B1 PROCESS FOR THE PREPARATION OF COMPOSITIONS FOR MODULATING A KINASE CASCADE AND METHODS OF USE THEREOF ATHENEX INC (US) 2018-05-02 EP claimed
EP-2114934-B1 COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE KINEX PHARMACEUTICALS LLC (US) 2015-10-21 EP claimed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 EP claimed
US-7939529-B2 Substantially pure 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide salts, solvates, hydrates, prodrugs; hyperproliferative disorders, cancers, pre-cancers, osteoporosis, cardiovascular disorders; bacterial, fungal, parasitic or viral infection KINEX PHARMACEUTICALS, LLC (US) 2011-05-10 US claimed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 WO claimed
EP-2155681-A1 PROCESS FOR THE PREPARATION OF COMPOSITIONS FOR MODULATING A KINASE CASCADE AND METHODS OF USE THEREOF Kinex Pharmaceuticals, LLC (US) 2010-02-24 EP claimed
WO-2008144045-A1 PROCESS FOR THE PREPARATION OF COMPOSITIONS FOR MODULATING A KINASE CASCADE AND METHODS OF USE THEREOF KINEX PHARMACEUTICALS, LLC (US) 2008-11-27 WO claimed
US-20080287436-A1 Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) 2008-11-20 US claimed