Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549250 | 0.87 | MAOB (0.68) | MAOBHRH3MAOAAPP | |
| SCHEMBL16687432 | 0.86 | ENPP2 (0.59) | MAOBHRH3MAOAENPP2FFAR1 | |
| SCHEMBL12420271 | 0.85 | ENPP2 (0.54) | MAOBENPP2APPF2 | |
| SCHEMBL2561397 | 0.85 | SMN1; SMN2 (0.48) | MAOBENPP2 | |
| SCHEMBL15332207 | 0.84 | MAOB (0.67) | MAOBENPP2APP | |
| SCHEMBL29952469 | 0.84 | MAOB (0.62) | MAOBMAOAENPP2APPF2 | |
| SCHEMBL177403 | 0.84 | MAOB (0.62) | MAOBMAOAENPP2FFAR1 | |
| SCHEMBL29954055 | 0.84 | MAOB (0.62) | MAOBMAOAENPP2FFAR1 | |
| SCHEMBL12182456 | 0.83 | MAOB (0.74) | MAOBHRH3MAOAAPP | |
| SCHEMBL29951430 | 0.83 | MAOB (0.63) | MAOBMAOAENPP2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-11-05 | — | — | US | disclosed |
| US-9024071-B2 | Therapeutic compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MAOB 780/4885HRH3 463/4885MAOA 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.