SCHEMBL16688342

SCHEMBL16688342

CO[C@@H]1OC(COS(=O)(=O)O)[C@@H](O[C@@H]2OC(C)[C@@H](O[C@@H]3OC(COS(=O)(=O)O)[C@@H](O[C@@H]4OC(C)[C@@H](O[C@@H]5OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C5NS(=O)(=O)O)[C@H](O)C4O)[C@H](OS(=O)(=O)O)C3NS(=O)(=O)O)C(O)[C@@H]2OS(=O)(=O)O)[C@H](O)C1NS(=O)(=O)O

nearest known ligand 0.81

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F10 P00742 4/20 0.81
FGF1 P05230 3/20 0.48
SERPINC1 P01008 3/20 0.48
F2 P00734 2/20 0.48
HPSE Q9Y251 9/20 0.42
PF4 P02776 2/20 0.41
IFNG P01579 1/20 0.39
BMP2 P12643 1/20 0.39
CCL2 P13500 1/20 0.39
VEGFA P15692 1/20 0.39
SELP P16109 1/20 0.39
BMP6 P22004 1/20 0.39
CXCL12 P48061 1/20 0.39
CCL11 P51671 1/20 0.39
WNT3A P56704 1/20 0.39
SELPLG Q14242 1/20 0.39
SHH Q15465 1/20 0.39
FGF2 P09038 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16688357 1.00 F10 (0.81) F10FGF1SERPINC1F2HPSE
SCHEMBL19618233 1.00 F10 (0.81) F10FGF1SERPINC1F2HPSE
SCHEMBL16688383 1.00 F10 (0.81) F10FGF1SERPINC1F2HPSE
SCHEMBL19618234 0.94 F10 (0.72) F10FGF1SERPINC1F2HPSE
Fondaparinux SCHEMBL17655218 0.90 F10 (1.00) F10FGF1SERPINC1F2HPSE
Fondaparinux SCHEMBL14227800 0.90 F10 (1.00) F10FGF1SERPINC1F2HPSE
Fondaparinux SCHEMBL1650579 0.90 F10 (1.00) F10FGF1SERPINC1F2HPSE
Fondaparinux SCHEMBL19619397 0.90 F10 (1.00) F10FGF1SERPINC1F2HPSE
Fondaparinux SCHEMBL15296579 0.90 F10 (1.00) F10FGF1SERPINC1F2HPSE
SCHEMBL10148985 0.82 F10 (0.85) F10FGF1SERPINC1F2HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822140-B2 Methods and intermediates for the preparation of fondaparinux ACADEMIA SINICA (TW) 2017-11-21 US disclosed
US-20150344513-A9 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX ACADEMIA SINICA (TW) 2015-12-03 US disclosed
US-20150126721-A1 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX ACADEMIA SINICA (TW) 2015-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344513-A9 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX F2, TBXA2R, PROC F10 27/4885FGF1 3310/4885SERPINC1 15/4885
US-20150126721-A1 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX F2, TBXA2R, PROC F10 27/4885FGF1 3310/4885SERPINC1 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.