SCHEMBL19618234

CC1O[C@@H](O[C@@H]2C(COS(=O)(=O)O)O[C@@H](O[C@H]3C(C)O[C@@H](O[C@@H]4C(COS(=O)(=O)O)O[C@@H](C)C(NS(=O)(=O)O)[C@H]4O)C(OS(=O)(=O)O)[C@@H]3O)C(NS(=O)(=O)O)[C@H]2OS(=O)(=O)O)C(O)[C@@H](O)[C@@H]1O[C@@H]1OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C1NS(=O)(=O)O

nearest known ligand 0.72

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	3/20	0.72

▸	F2	P00734	1/20	0.48

▸	SERPINC1	P01008	1/20	0.48

▸	HPSE	Q9Y251	12/20	0.43

▸	FGF1	P05230	3/20	0.42

▸	PF4	P02776	2/20	0.42

▸	IFNG	P01579	1/20	0.39

▸	BMP2	P12643	1/20	0.39

▸	CCL2	P13500	1/20	0.39

▸	VEGFA	P15692	1/20	0.39

▸	SELP	P16109	1/20	0.39

▸	BMP6	P22004	1/20	0.39

▸	CXCL12	P48061	1/20	0.39

▸	CCL11	P51671	1/20	0.39

▸	WNT3A	P56704	1/20	0.39

▸	SELPLG	Q14242	1/20	0.39

▸	SHH	Q15465	1/20	0.39

▸	FGF2	P09038	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16688357	0.94	F10 (0.81)	F10F2SERPINC1HPSEFGF1
SCHEMBL16688342	0.94	F10 (0.81)	F10F2SERPINC1HPSEFGF1
SCHEMBL19618233	0.94	F10 (0.81)	F10F2SERPINC1HPSEFGF1
SCHEMBL16688383	0.94	F10 (0.81)	F10F2SERPINC1HPSEFGF1
SCHEMBL15996539	0.87	F10 (0.56)	F10F2SERPINC1HPSEFGF1
SCHEMBL15996755	0.84	F10 (0.78)	F10F2SERPINC1HPSEPF4
Fondaparinux SCHEMBL19619397	0.84	F10 (1.00)	F10F2SERPINC1HPSEFGF1
Fondaparinux SCHEMBL15296579	0.84	F10 (1.00)	F10F2SERPINC1HPSEFGF1
Fondaparinux SCHEMBL14227800	0.84	F10 (1.00)	F10F2SERPINC1HPSEFGF1
Fondaparinux SCHEMBL17655218	0.84	F10 (1.00)	F10F2SERPINC1HPSEFGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9822140-B2	Methods and intermediates for the preparation of fondaparinux	ACADEMIA SINICA (TW)	2017-11-21	—	—	US	disclosed