Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL11232548 | 0.89 | CA1 (0.42) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL5694604 | 0.88 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28075164 | 0.88 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28128452 | 0.88 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL2703945 | 0.88 | TDP1 (0.55) | TDP1CA12CA1CA2GLA | |
| Biphenyl SCHEMBL2505116 | 0.86 | LMNA (0.42) | TDP1LMNATSHRTRPA1CYP1A2 | |
| Phenol SCHEMBL27994753 | 0.86 | TDP1 (0.48) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28214512 | 0.86 | TDP1 (0.52) | TDP1CA12CA1CA2GLA | |
| Benzene SCHEMBL2865296 | 0.85 | TDP1 (0.53) | TDP1LMNATSHRTRPA1POLB | |
| Phenol SCHEMBL99177 | 0.85 | CA12 (0.58) | TDP1CA12CA1CA2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257790-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | INTEGRATED DNA TECHNOLOGIES, INC. | 2023-08-17 | — | — | US | claimed |
| WO-2023147547-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2023-08-03 | — | — | WO | claimed |
| CN-110950581-A | High-water-resistance real stone paint for building exterior wall and preparation method thereof | 安徽领珂数据科技有限公司 | 2020-04-03 | — | — | CN | claimed |
| EP-2705157-A1 | LIGATION ENHANCEMENT | New England Biolabs, Inc. (US) | 2014-03-12 | — | — | EP | claimed |
| WO-2013022504-A1 | LIGATION ENHANCEMENT | NEW ENGLAND BIOLABS, INC. (US) | 2013-02-14 | — | — | WO | claimed |
| US-20120283144-A1 | Ligation Enhancement | NEW ENGLAND BIOLABS, INC. (US) | 2012-11-08 | — | — | US | claimed |
| US-6670319-B1 | organic solvent, binary co-solvent comprising an alkyl diphenyl solvent and a co-solvent; an amine oxide surfactant constituent; optionally, a further detersive surfactant, hard surface cleaning compound | RECKITT BENCKISER INC. | 2003-12-30 | — | — | US | claimed |
| US-6642197-B1 | Aqueous concentrated liquid hard surface cleaning composition which blooms when added to larger volume of water, comprising organic solvent, germicide, and binary system comprising alkyldiphenyl solvent and at least one cosolvent | RECKITT BENCKISER INC. | 2003-11-04 | — | — | US | claimed |
| US-20230257790-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | INTEGRATED DNA TECHNOLOGIES, INC. | 2023-08-17 | — | — | US | disclosed |
| WO-2023147547-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-110950581-A | High-water-resistance real stone paint for building exterior wall and preparation method thereof | 安徽领珂数据科技有限公司 | 2020-04-03 | — | — | CN | disclosed |
| EP-2697353-B1 | ENVIRONMENTALLY FRIENDLY, MULTI-PURPOSE REFLUXING CLEANER | AMERICAN STERILIZER CO (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2705157-B1 | LIGATION ENHANCEMENT | NEW ENGLAND BIOLABS INC (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9499811-B2 | Ligation enhancement | NEW ENGLAND BIOLABS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-4759867-A | Consists of an acid surfactants-benzene sulfonic acids, alkylated diphenyl oxide disulfonates and mixture, water, solvent, and quaternary ammonium compound as microbiocide | THE CLOROX COMPANY (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0131394-B1 | HARD SURFACE ACID CLEANER | The Clorox Company (US) | 1988-02-17 | — | — | EP | disclosed |
| US-4707232-A | PROTECTIVE COATINGS | BASF FARBEN & FASERN AG (DE) | 1987-11-17 | — | — | US | disclosed |
| US-4707221-A | Sheets having improved stiffness from fiber, latex and coalescing agent | THE DOW CHEMICAL COMPANY (US) | 1987-11-17 | — | — | US | disclosed |
| US-4661541-A | Alcohol-modified polyepoxides, their preparation and their use in curable mixtures | BASF FARBEN & FASERN AG (DE) | 1987-04-28 | — | — | US | disclosed |
| EP-0131394-A2 | Hard surface acid cleaner | The Clorox Company (US) | 1985-01-16 | — | — | EP | disclosed |