Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL35797 | 0.92 | TDP1 (0.62) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL18285762 | 0.92 | TDP1 (0.62) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL4936361 | 0.92 | TDP1 (0.62) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL6135352 | 0.89 | TDP1 (0.59) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL8231638 | 0.89 | TDP1 (0.59) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Biphenyl SCHEMBL2505116 | 0.87 | LMNA (0.42) | TDP1TSHRALDH1A1LMNATRPA1 | |
| Propylene Glycol SCHEMBL93425 | 0.86 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL3418653 | 0.86 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL28174906 | 0.86 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA | |
| Propylene Glycol SCHEMBL15659730 | 0.86 | TDP1 (0.56) | TDP1TSHRALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150747-B2 | Self designed fashion wear and other articles | MY DESIGN LIMITED (HK) | 2015-10-06 | — | — | US | claimed |
| US-20100320102-A1 | SELF DESIGNED FASHION WEAR AND OTHER ARTICLES | MY DESIGN LTD. (HK) | 2010-12-23 | — | — | US | claimed |
| EP-2084238-A1 | SELF DESIGNED FASHION WEAR AND OTHER ARTICLES | My Design Limited (HK) | 2009-08-05 | — | — | EP | claimed |
| WO-2008050338-A1 | SELF DESIGNED FASHION WEAR AND OTHER ARTICLES | MY DESIGN LIMITED (HK) | 2008-05-02 | — | — | WO | claimed |
| US-9150747-B2 | Self designed fashion wear and other articles | MY DESIGN LIMITED (HK) | 2015-10-06 | — | — | US | disclosed |
| US-20100320102-A1 | SELF DESIGNED FASHION WEAR AND OTHER ARTICLES | MY DESIGN LTD. (HK) | 2010-12-23 | — | — | US | disclosed |
| EP-2084238-A1 | SELF DESIGNED FASHION WEAR AND OTHER ARTICLES | My Design Limited (HK) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008050338-A1 | SELF DESIGNED FASHION WEAR AND OTHER ARTICLES | MY DESIGN LIMITED (HK) | 2008-05-02 | — | — | WO | disclosed |