Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12798265 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDRCE1USP2 | |
| SCHEMBL11893819 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDRCE1USP2 | |
| SCHEMBL1666506 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDRCE1USP2 | |
| Acetic Acid SCHEMBL11893957 | 0.96 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDRCE1USP2 | |
| Acetic Acid SCHEMBL11893956 | 0.96 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDRCE1USP2 | |
| SCHEMBL2154639 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDRCE1HSD17B10 | |
| SCHEMBL13163161 | 0.86 | HTR7 (0.50) | ALDH1A1KDM4EHPGDCHRM1GNRHR | |
| SCHEMBL12799245 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRCE1HSD17B10 | |
| SCHEMBL5670080 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRCE1HSD17B10 | |
| SCHEMBL5670087 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRCE1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485728-A1 | WNT PATHWAY ANTAGONISTS | Siena Biotech S.p.a. (IT) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042145-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2011-04-14 | — | — | WO | disclosed |