Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250573 | 0.77 | SMN1; SMN2 (0.33) | TDP1SMN1; SMN2 | |
| SCHEMBL9313404 | 0.76 | TDP1 (0.32) | TDP1SMN1; SMN2 | |
| SCHEMBL27598566 | 0.74 | TDP1 (0.45) | TDP1TSHRSMN1; SMN2 | |
| SCHEMBL3151254 | 0.74 | TDP1 (0.45) | TDP1TSHRSMN1; SMN2 | |
| SCHEMBL8232558 | 0.74 | TDP1 (0.39) | TDP1TSHRSMN1; SMN2 | |
| SCHEMBL9314607 | 0.73 | CASP1 (0.30) | TDP1 | |
| SCHEMBL21250568 | 0.73 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL9314639 | 0.72 | — | — | |
| SCHEMBL8232555 | 0.72 | TDP1 (0.35) | TDP1TSHRSMN1; SMN2 | |
| SCHEMBL9696715 | 0.70 | TDP1 (0.31) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | THE UNIVERSITY OF HONG KONG (CN) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | SCD, SCD5, FASN | TDP1 4228/4885TSHR 2372/4885SMN1; SMN2 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.