SCHEMBL16690160

SCHEMBL16690160

CCCCC(=NOC(C)=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.45
ALDH1A1 P00352 7/20 0.45
KMT2A Q03164 5/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
ALOX12 P18054 1/20 0.44
MAPK1 P28482 2/20 0.43
LMNA P02545 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
BCL9 O00512 1/20 0.42
CTNNB1 P35222 1/20 0.42
MEN1 O00255 2/20 0.42
POLB P06746 2/20 0.42
MGLL Q99685 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16690156 0.95 ALDH1A1 (0.51) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL16690175 0.89 HDAC3 (0.46) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL16690182 0.87 MAPK1 (0.47) MAPTALDH1A1KMT2AMAPK1MEN1
SCHEMBL9962618 0.85 ALDH1A1 (0.48) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL16690176 0.85 ALDH1A1 (0.50) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL17973404 0.82 MAPK1 (0.45) MAPTALDH1A1KMT2ASMN1; SMN2MAPK1
SCHEMBL16690166 0.81 MAPT (0.51) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E
SCHEMBL16690170 0.79 MAPK1 (0.53) MAPTALDH1A1KMT2AMAPK1LMNA
SCHEMBL16581243 0.79 L3MBTL1 (0.48) MAPTALDH1A1KMT2AKDM4ELMNA
SCHEMBL16690228 0.79 MAPT (0.49) MAPTALDH1A1KMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064958-A1 NOVEL OXIME ESTER BIPHENYL COMPOUND, PHOTO INITIATOR AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME 한국화학연구원 2015-05-07 WO disclosed