SCHEMBL16690489

SCHEMBL16690489

O=S(=O)(Oc1cccc2ccc(-c3c4ccccc4c(-c4ccccc4)c4ccccc34)cc12)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
ESR1 P03372 4/20 0.36
PDE4A P27815 3/20 0.35
PDE4C Q08493 3/20 0.35
PDE4D Q08499 3/20 0.35
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTPN1 P18031 2/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16690527 0.88 ADORA2A (0.37) ADORA2AADORA1ESR1PDE4APDE4C
SCHEMBL13098729 0.83 CA1 (0.38) ADORA2AADORA1ESR1ALDH1A1MEN1
Biphenyl SCHEMBL4019546 0.82 ALDH1A1 (0.42) ADORA2AADORA1PDE4APDE4CPDE4D
SCHEMBL25634034 0.82 MAPT (0.39) ADORA2AADORA1PDE4APDE4CPDE4D
SCHEMBL29937164 0.82 ALDH1A1 (0.46) ESR1ALDH1A1MEN1RAB9AKMT2A
SCHEMBL1056365 0.82 ALDH1A1 (0.46) ESR1ALDH1A1MEN1RAB9AKMT2A
SCHEMBL14506136 0.82 ADORA2A (0.42) ADORA2AADORA1ESR1PDE4APDE4C
SCHEMBL25024158 0.81 MAPT (0.39) ADORA2AADORA1PDE4APDE4CPDE4D
SCHEMBL13016398 0.81 ADORA2A (0.41) ADORA2AADORA1ESR1ALDH1A1MAPT
SCHEMBL11904137 0.81 CA2 (0.41) ADORA2AADORA1ESR1SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064560-A1 ANTHRACENE COMPOUND; LIGHT-EMITTING-LAYER MATERIAL; AND ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAME JNC株式会社 2015-05-07 WO disclosed