Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | COMT | P21964 | 1/20 | 0.58 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609366 | 0.92 | MEN1 (0.68) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL4609378 | 0.92 | MEN1 (0.68) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL16689663 | 0.91 | KMT2A (0.57) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL16690921 | 0.91 | MEN1 (0.59) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL16690922 | 0.84 | MEN1 (0.52) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL1405285 | 0.83 | MEN1 (0.77) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL16160387 | 0.83 | FTO (0.77) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL14573318 | 0.83 | MEN1 (0.77) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL1405287 | 0.83 | MEN1 (0.77) | MEN1KMT2AABCC3ABCC4ABCB11 | |
| SCHEMBL16689658 | 0.83 | KMT2A (0.58) | MEN1KMT2AABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266823-B2 | Compositions and methods for the treatment of parkinson's disease | CELLIX BIO PRIVATE LIMITED (IN) | 2016-02-23 | — | — | US | disclosed |
| US-20150126591-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE | CELLIX BIO PRIVATE LIMITED (IN) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126591-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE | PARK7, HTT, SNCA | MEN1 1288/4885KMT2A 4311/4885ABCC3 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.