Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670829 | 0.92 | POLB (0.41) | POLBPARP14PARP10ALDH1A1ABCB1 | |
| SCHEMBL13967554 | 0.90 | POLB (0.45) | POLBPARP14PARP10ALDH1A1KDM4E | |
| SCHEMBL1668846 | 0.86 | PARP14 (0.46) | POLBPARP14PARP10ALDH1A1KDM4E | |
| SCHEMBL1668831 | 0.81 | PARP14 (0.40) | POLBPARP14PARP10ALDH1A1KDM4E | |
| SCHEMBL1671063 | 0.80 | NAMPT (0.39) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL1668681 | 0.78 | MGLL (0.48) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL13967555 | 0.77 | PARP14 (0.42) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL13967549 | 0.76 | PARP14 (0.46) | POLBPARP14PARP10ALDH1A1KDM4E | |
| SCHEMBL15788505 | 0.76 | PARP14 (0.41) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL1668933 | 0.75 | PARP14 (0.44) | PARP14PARP10ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |