Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668831 | 0.88 | PARP14 (0.40) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL13836299 | 0.87 | PARP14 (0.48) | PARP14PARP10 | |
| SCHEMBL1671688 | 0.87 | PARP14 (0.48) | PARP14PARP10 | |
| SCHEMBL13967549 | 0.87 | PARP14 (0.46) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL1669148 | 0.86 | POLB (0.42) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL1668681 | 0.84 | MGLL (0.48) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL1668601 | 0.81 | PARP14 (0.44) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL14879836 | 0.80 | MGLL (0.51) | PARP14PARP10KMT2ACCR3 | |
| SCHEMBL1668837 | 0.80 | MGLL (0.56) | — | |
| SCHEMBL1670879 | 0.80 | KMT2A (0.47) | PARP14TSHRNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |