Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148065 | 0.74 | LTB4R (0.44) | DRD2DRD3CYP19A1 | |
| SCHEMBL22439161 | 0.73 | DRD2 (0.43) | DRD2DRD3KDM1AHCRTR2CYP19A1 | |
| SCHEMBL31136565 | 0.73 | DRD2 (0.43) | DRD2DRD3HCRTR2CYP19A1LMNA | |
| SCHEMBL31603066 | 0.73 | DRD2 (0.43) | DRD2DRD3HCRTR2CYP19A1LMNA | |
| SCHEMBL31603070 | 0.73 | DRD2 (0.43) | DRD2DRD3HCRTR2CYP19A1LMNA | |
| SCHEMBL30015979 | 0.73 | DRD2 (0.43) | DRD2DRD3KDM1AHCRTR2CYP19A1 | |
| SCHEMBL29340304 | 0.73 | DRD2 (0.43) | DRD2DRD3KDM1AHCRTR2CYP19A1 | |
| SCHEMBL2610191 | 0.72 | DRD2 (0.41) | DRD2DRD3HCRTR2CYP19A1LMNA | |
| SCHEMBL2610213 | 0.72 | DRD2 (0.41) | DRD2DRD3HCRTR2CYP19A1LMNA | |
| SCHEMBL2112722 | 0.72 | DRD2 (0.41) | DRD2DRD3HCRTR2CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066371-A1 | SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS | FORUM PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |