SCHEMBL16693172

SCHEMBL16693172

N[n+]1ccc(CO)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL904427 0.72
SCHEMBL21490432 0.72 CHKA (0.56)
SCHEMBL10044408 0.72
SCHEMBL9481458 0.72
SCHEMBL22228647 0.72 RAPGEF4 (0.39)
SCHEMBL41775 0.71 TSHR (0.67)
Hydrochloric Acid SCHEMBL10766835 0.69 TSHR (0.42)
SCHEMBL294241 0.69 CHKA (0.52)
SCHEMBL31672218 0.65 TSHR (0.59)
SCHEMBL54121 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727940-A1 DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF Linkcure Therapeutics (KY) 2026-04-22 EP disclosed
WO-2024255810-A1 DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF HANGZHOU GLUBIO PHARMACEUTICAL CO., LTD (CN) 2024-12-19 WO disclosed
WO-2020153676-A1 A FUSED RING HETEROARYL COMPOUND AS AN ALK4/5 INHIBITOR BISICHEM CO., LTD. (KR) 2020-07-30 WO disclosed
WO-2015066371-A1 SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS FORUM PHARMACEUTICALS, INC. (US) 2015-05-07 WO disclosed