SCHEMBL16694041

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1965264	0.86	MCL1 (0.56)	MCL1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL16694221	0.86	MCL1 (0.41)	MCL1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL29030439	0.80	MCL1 (0.40)	MCL1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL10165329	0.80	KDM4E (0.45)	MCL1CA12CA1CA2CA7
	SCHEMBL27964359	0.78	CA12 (0.54)	CA12CA1CA2CA7CA9
	SCHEMBL6245932	0.77	UTS2R (0.43)	GABRA1GABRA3CA12CA1CA2
	SCHEMBL19823831	0.76	MCL1 (0.38)	MCL1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL10413915	0.76	TDP1 (0.41)	MCL1TAS1R3TAS1R1TRPA1MAPT
	SCHEMBL21052519	0.75	MCL1 (0.57)	MCL1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL940632	0.74	MCL1 (0.48)	MCL1GABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.