Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 10/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484038 | 0.83 | TDP1 (0.62) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL3058890 | 0.83 | TDP1 (0.45) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL901472 | 0.82 | TDP1 (0.72) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL19801525 | 0.81 | TDP1 (0.44) | TDP1POLBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL855813 | 0.81 | HTT (0.44) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL8610246 | 0.80 | TDP1 (0.69) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| Sumiki'S Acid SCHEMBL50822 | 0.80 | TDP1 (1.00) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| Sumiki'S Acid SCHEMBL29706392 | 0.80 | TDP1 (1.00) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL18640579 | 0.79 | CA1 (0.52) | TDP1POLBSMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL18554594 | 0.78 | TDP1 (0.67) | TDP1POLBSMN1; SMN2HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057707-A | Preparation method of N-4-indolyl-2-furancarboxamide compound | 上海应用技术大学 | 2022-02-18 | — | — | CN | claimed |
| CN-111499878-A | Antitumor polymer bonding medicine with synergistic effect and preparation method thereof | 成都吱吖科技有限公司 | 2020-08-07 | — | — | CN | claimed |
| EP-3666764-A1 | METHOD FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND FOR THE PREPARATION OF THE DIALKYL ESTER OF 2,5-FURANDICARBOXYLIC ACID | Furanix Technologies B.V (NL) | 2020-06-17 | — | — | EP | claimed |
| US-10392358-B2 | Oxidation chemistry on furan aldehydes | MICROMIDAS, INC. (US) | 2019-08-27 | — | — | US | claimed |
| US-20180265488-A1 | OXIDATION CHEMISTRY ON FURAN ALDEHYDES | MICROMIDAS, INC. (US) | 2018-09-20 | — | — | US | claimed |
| CN-108349920-A | OXIDATION CHEMISTRY ON FURAN ALDEHYDES | 微麦德斯公司 | 2018-07-31 | — | — | CN | claimed |
| WO-2017049211-A1 | OXIDATION CHEMISTRY ON FURAN ALDEHYDES | MICROMIDAS, INC. (US) | 2017-03-23 | — | — | WO | claimed |
| CN-102666521-B | Method for the preparation of 2,5-furandicarboxylic acid and for the preparation of the dialkyl ester of 2,5-furandicarboxylic acid | FURANIX TECHNOLOGIES BV | 2015-04-29 | — | — | CN | claimed |
| US-8865921-B2 | Method for the preparation of 2,5-furandicarboxylic acid and for the preparation of the dialkyl ester of 2,5-furandicarboxylic acid | FURANIX TECHNOLOGIES B.V. (NL) | 2014-10-21 | — | — | US | claimed |
| US-20120271060-A1 | METHOD FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND FOR THE PREPARATION OF THE DIALKYL ESTER OF 2,5-FURANDICARBOXYLIC ACID | FURANIX TECHNOLOGIES B.V. (NL) | 2012-10-25 | — | — | US | claimed |
| CN-102666521-A | Method for the preparation of 2,5-furandicarboxylic acid and for the preparation of the dialkyl ester of 2,5-furandicarboxylic acid | FURANIX TECHNOLOGIES BV | 2012-09-12 | — | — | CN | claimed |
| EP-2486028-A1 | METHOD FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND FOR THE PREPARATION OF THE DIALKYL ESTER OF 2,5-FURANDICARBOXYLIC ACID | Furanix Technologies B.V. (NL) | 2012-08-15 | — | — | EP | claimed |
| WO-2011043661-A1 | METHOD FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND FOR THE PREPARATION OF THE DIALKYL ESTER OF 2,5-FURANDICARBOXYLIC ACID | FURANIX TECHNOLOGIES B.V. (NL) | 2011-04-14 | — | — | WO | claimed |
| US-12459929-B2 | GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use | CARMOT THERAPEUTICS INC. (US) | 2025-11-04 | — | — | US | disclosed |
| EP-4563199-A2 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| US-20250154137-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. | 2025-05-15 | — | — | US | disclosed |
| US-4185147-A | Production of amino-silicate compounds, condensation resinous products and foam | BLOUNT DAVID H | 1980-01-22 | — | — | US | disclosed |
| US-4146509-A | ORGANIC AMMONIUM COMPOUNDS USED AS POLYMERIZATION CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4142030-A | POLYURETHANE-SILICATE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4042536-A | POLYISOCYANATE, SILICIC ACID, XEROGEL | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392358-B2 | Oxidation chemistry on furan aldehydes | AOX1, ALOX5, CBR1 | TDP1 2488/4885POLB 2337/4885SMN1; SMN2 4547/4885 |
| US-20250154137-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | GLP1R, GCGR, GIPR | TDP1 3659/4885POLB 4784/4885SMN1; SMN2 2952/4885 |
| US-12459929-B2 | GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use | GLP1R, GCGR, GIPR | TDP1 3659/4885POLB 4784/4885SMN1; SMN2 2952/4885 |
| US-20180265488-A1 | OXIDATION CHEMISTRY ON FURAN ALDEHYDES | AOX1, ALOX5, CBR1 | TDP1 2488/4885POLB 2337/4885SMN1; SMN2 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.