Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786818 | 0.93 | POLB (0.59) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL25754033 | 0.91 | POLB (0.58) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL17122140 | 0.91 | POLB (0.58) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL17122136 | 0.90 | POLB (0.56) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL16248673 | 0.89 | POLB (0.74) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL19051966 | 0.89 | POLB (0.74) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL21447399 | 0.88 | POLB (0.56) | POLBP2RY1ENPP1ADORA1 | |
| SCHEMBL18745523 | 0.87 | POLB (0.54) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL20428118 | 0.87 | P2RY1 (0.63) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL24325561 | 0.87 | POLB (0.53) | POLBP2RY1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015062743-A1 | MEANS AND METHODS FOR THE TREATMENT OF NEPHROPATHY | NOXXON PHARMA AG (DE) | 2015-05-07 | — | — | WO | disclosed |