Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | DTYMK | P23919 | 2/20 | 0.53 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.53 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.53 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25766886 | 0.92 | P2RY1 (0.62) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL16695892 | 0.91 | POLB (0.59) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL25786818 | 0.91 | POLB (0.59) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL26068420 | 0.91 | POLB (0.59) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL17122140 | 0.90 | POLB (0.58) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL18745523 | 0.89 | POLB (0.54) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL17122136 | 0.88 | POLB (0.56) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL16248673 | 0.87 | POLB (0.74) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL19051966 | 0.87 | POLB (0.74) | POLBP2RY1ENPP1P2RY2P2RX1 | |
| SCHEMBL24325561 | 0.87 | POLB (0.53) | POLBP2RY1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | POLB 2/4885P2RY1 1172/4885ENPP1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.