Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 6/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16696129 | 0.92 | CYP3A4 (0.61) | CYP3A4C5AR1CYP2D6 | |
| SCHEMBL16696030 | 0.92 | CYP3A4 (0.45) | CYP3A4C5AR1CACNA1GCACNA1HCYP2D6 | |
| SCHEMBL16696112 | 0.85 | CYP3A4 (0.66) | CYP3A4C5AR1CACNA1GCACNA1HNPSR1 | |
| SCHEMBL16696051 | 0.83 | CYP3A4 (0.52) | CYP3A4C5AR1CACNA1GCACNA1HNPSR1 | |
| SCHEMBL16696065 | 0.83 | CYP3A4 (0.52) | CYP3A4C5AR1CACNA1GCACNA1HOPRL1 | |
| SCHEMBL16696119 | 0.83 | CYP3A4 (0.49) | CYP3A4C5AR1CACNA1GCACNA1HNPSR1 | |
| SCHEMBL16696092 | 0.83 | OPRL1 (0.48) | CYP3A4C5AR1NPSR1ALDH1A1OPRL1 | |
| SCHEMBL16696169 | 0.83 | CACNA1G (0.50) | CYP3A4C5AR1CACNA1GCACNA1HNPSR1 | |
| SCHEMBL16696093 | 0.82 | CYP3A4 (0.49) | CYP3A4C5AR1CACNA1GCACNA1HALDH1A1 | |
| SCHEMBL16696159 | 0.82 | OPRL1 (0.49) | CYP3A4OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065336-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |