Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078996 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2NPY1RNPY2RRAB9AHPGD | |
| SCHEMBL6004344 | 0.87 | SMN1; SMN2 (0.73) | SMN1; SMN2NPY1RNPY2RRAB9AHPGD | |
| SCHEMBL7407182 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AHPGDNPC1CYP1A2 | |
| SCHEMBL16654381 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AHPGDNPC1CYP1A2 | |
| SCHEMBL13506223 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AHPGDNPC1CYP1A2 | |
| SCHEMBL13334587 | 0.79 | MAPT (0.58) | SMN1; SMN2NPY1RNPY2RRAB9AHPGD | |
| SCHEMBL27346145 | 0.78 | NPY1R (0.74) | NPY1RNPY2RRAB9AHPGDCYP1A2 | |
| SCHEMBL14513419 | 0.78 | NLRP3 (0.65) | SMN1; SMN2RAB9AHPGDNPC1CYP1A2 | |
| SCHEMBL30190594 | 0.78 | RAB9A (0.51) | SMN1; SMN2RAB9AHPGDNPC1CYP1A2 | |
| SCHEMBL7815282 | 0.78 | RAB9A (0.68) | SMN1; SMN2RAB9AHPGDNPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |