Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13734244 | 0.77 | HSD17B10 (0.59) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL30395456 | 0.77 | HSD17B10 (0.76) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL459354 | 0.77 | HSD17B10 (0.76) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| Hydrochloric Acid SCHEMBL11554371 | 0.76 | HSD17B10 (0.74) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL899864 | 0.74 | HSD17B10 (0.52) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL16698299 | 0.73 | GPBAR1 (0.65) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL16697481 | 0.71 | HSD17B10 (0.52) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL29059059 | 0.71 | MAPT (1.00) | MAPTHSD17B10CYP2C19LMNAKMT2A | |
| SCHEMBL27910275 | 0.70 | HSD17B10 (0.78) | MAPTHSD17B10CYP2C19GPBAR1LMNA | |
| SCHEMBL16698055 | 0.69 | HSD17B10 (0.53) | MAPTHSD17B10CYP2C19GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | VIROCURA THERAPEUTICS INC (CA) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | EIF2AK2, GTF3C4, GTF3C1 | MAPT 4607/4885HSD17B10 1479/4885CYP2C19 1782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.