Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471766 | 0.83 | PTGS1 (0.51) | GPBAR1ALDH1A1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL16697750 | 0.79 | GPBAR1 (0.67) | HSD17B10GPBAR1ALDH1A1CYP2C19LMNA | |
| SCHEMBL315858 | 0.78 | HSD17B10 (0.76) | HSD17B10GPBAR1ALDH1A1CYP2C19LMNA | |
| SCHEMBL32679558 | 0.78 | HSD17B10 (0.76) | HSD17B10GPBAR1ALDH1A1CYP2C19LMNA | |
| SCHEMBL2475005 | 0.75 | LMNA (0.52) | GPBAR1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL16698337 | 0.74 | MEN1 (0.50) | HSD17B10GPBAR1ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL16698339 | 0.74 | ADORA3 (0.55) | HSD17B10ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16698335 | 0.74 | ADORA3 (0.55) | HSD17B10ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4010252 | 0.74 | POLB (0.68) | ALDH1A1LMNASCN9AMAPTHPGD | |
| SCHEMBL4947186 | 0.74 | GPBAR1 (0.43) | GPBAR1CYP2C19CYP2C9SCN9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | VIROCURA THERAPEUTICS INC (CA) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | EIF2AK2, GTF3C4, GTF3C1 | HSD17B10 1479/4885GPBAR1 191/4885ALDH1A1 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.