Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 3/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16698330 | 0.90 | CTNNB1 (0.60) | CTNNB1WNT3ACCR2RAB9ASMN1; SMN2 | |
| SCHEMBL16697639 | 0.80 | RAB9A (0.62) | CTNNB1WNT3ACCR2RAB9ASMN1; SMN2 | |
| SCHEMBL16697642 | 0.80 | RAB9A (0.62) | CTNNB1WNT3ACCR2RAB9ASMN1; SMN2 | |
| SCHEMBL16701197 | 0.78 | NPC1 (0.49) | RAB9ASMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL16698353 | 0.77 | RAB9A (0.69) | CTNNB1WNT3ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL16698156 | 0.75 | ALDH1A1 (0.51) | CTNNB1WNT3ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL16697358 | 0.73 | RAB9A (0.49) | CTNNB1WNT3ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16697151 | 0.71 | RAB9A (0.47) | CTNNB1WNT3ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16697795 | 0.71 | RAB9A (0.47) | CTNNB1WNT3ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16698331 | 0.70 | CTNNB1 (0.60) | CTNNB1WNT3ARAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | VIROCURA THERAPEUTICS INC (CA) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | EIF2AK2, GTF3C4, GTF3C1 | CTNNB1 4006/4885WNT3A 3259/4885CCR2 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.