Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301544 | 0.87 | ALDH1A1 (0.58) | NPC1CYP2C9PDCD1CD274TSHR | |
| SCHEMBL29480096 | 0.87 | ALDH1A1 (0.58) | NPC1CYP2C9PDCD1CD274TSHR | |
| SCHEMBL30788746 | 0.87 | ALDH1A1 (0.58) | NPC1CYP2C9PDCD1CD274TSHR | |
| SCHEMBL27636054 | 0.86 | SCN1A (0.62) | NPC1PDCD1CD274PDK2SCN1A | |
| SCHEMBL16698129 | 0.84 | NPC1 (0.58) | NPC1CYP2C9PDCD1CD274PDK2 | |
| SCHEMBL399125 | 0.83 | NPC1 (0.56) | NPC1CYP2C9PDCD1CD274PDK2 | |
| SCHEMBL137907 | 0.82 | NPC1 (0.62) | NPC1CYP2C9PDCD1CD274PDK2 | |
| SCHEMBL6437163 | 0.79 | SLC6A3 (0.59) | CYP2C9CYP3A4ALOX12TSHRMYC | |
| SCHEMBL542115 | 0.79 | ALDH1A1 (0.54) | CYP2C9CYP3A4ALOX12MYCALDH1A1 | |
| SCHEMBL2597548 | 0.79 | SCN1A (0.40) | NPC1CYP2C9CYP3A4ALOX12SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | VIROCURA THERAPEUTICS INC (CA) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133495-A1 | Substituted Acyloxyamidines as HCV NS3/4A Inhibitors | EIF2AK2, GTF3C4, GTF3C1 | NPC1 922/4885CYP2C9 1194/4885PDCD1 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.