Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL16699395

CCCCCc1[nH]cc[n+]1C.O=C([O-])C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 3/20 0.40
FAAH O00519 6/20 0.38
GPR84 Q9NQS5 2/20 0.36
KCNH2 Q12809 6/20 0.35
CES1 P23141 3/20 0.33
CES2 O00748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL535019 0.96 CCR5 (0.36) CCR5FAAHGPR84CES1CES2
Trifluoroacetic Acid SCHEMBL16700895 0.90 CCR5 (0.32) CCR5
Acetic Acid SCHEMBL1660879 0.87 GPR84 (0.38) GPR84KCNH2CES1CES2
Acetic Acid SCHEMBL232904 0.87 GPR84 (0.38) GPR84KCNH2CES1CES2
Acetic Acid SCHEMBL15575254 0.87 GPR84 (0.38) GPR84KCNH2CES1CES2
Bicarbonate SCHEMBL7004683 0.87 GPR84 (0.38) GPR84KCNH2CES1CES2
Pivalate SCHEMBL15287009 0.86 NPC1 (0.32) GPR84
SCHEMBL8589327 0.84
Trifluoroacetic Acid SCHEMBL4023809 0.84 HIF1A (0.32) CCR5
Acetic Acid SCHEMBL232563 0.84 GPR84 (0.33) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP claimed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP claimed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US claimed
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP disclosed
US-10227274-B2 Separations with ionic liquid solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-03-12 US disclosed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP disclosed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US disclosed