Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL16699728

Cc1nc(-c2ccccc2)cn1C.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 5/20 0.44
SCN9A Q15858 1/20 0.43
NPC1 O15118 5/20 0.41
RAB9A P51151 5/20 0.41
MAPT P10636 2/20 0.41
PDE10A Q9Y233 7/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
NFKB1 P19838 2/20 0.40
NFKB2 Q00653 2/20 0.40
RELA Q04206 2/20 0.40
TP53 P04637 2/20 0.40
ALOX15 P16050 1/20 0.40
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
CHRNA7 P36544 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL16699839 0.85 KDM4E (0.42) ALDH1A1KDM4ESCN9ANPC1RAB9A
SCHEMBL8830111 0.85 KDM4E (0.49) ALDH1A1KDM4ENPC1RAB9AMAPT
SCHEMBL16700744 0.81 KDM4E (0.46) ALDH1A1KDM4ENPC1RAB9AMAPT
Nitric Acid SCHEMBL16699970 0.80 KDM4E (0.45) ALDH1A1KDM4ENPC1RAB9AMAPT
SCHEMBL27917384 0.80 KDM4E (0.44) ALDH1A1KDM4ENPC1RAB9AMAPT
SCHEMBL3441075 0.76 CHEK1 (0.51) ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL724249 0.75 PDE3B (0.55) ALDH1A1KDM4ENPC1RAB9AMAPT
Trifluoroacetic Acid SCHEMBL16699933 0.73 KDM1A (0.34) PDE10ATP53
SCHEMBL6718823 0.73 TLR8 (0.53) ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL14077066 0.72 RAB9A (0.50) ALDH1A1KDM4ENPC1RAB9APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP claimed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP claimed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US claimed
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP disclosed
US-10227274-B2 Separations with ionic liquid solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-03-12 US disclosed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP disclosed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US disclosed