Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075635 | 0.83 | MAPT (0.48) | MEN1KMT2AMAPK1KDM4ERXFP1 | |
| SCHEMBL1667624 | 0.83 | KDM4E (0.37) | MEN1KMT2AKDM4ENPSR1TDP2 | |
| SCHEMBL12377649 | 0.77 | HTT (0.39) | MAOAMAOBMEN1KMT2AMAPK1 | |
| SCHEMBL1668123 | 0.76 | MAPT (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30176370 | 0.76 | KDM4E (0.40) | MEN1KMT2AMAPK1KDM4ECYP3A4 | |
| SCHEMBL23886817 | 0.76 | KDM4E (0.40) | MEN1KMT2AMAPK1KDM4ECYP3A4 | |
| SCHEMBL1667649 | 0.73 | L3MBTL1 (0.49) | KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12387042 | 0.71 | MEN1 (0.38) | MAOBMEN1KMT2AMAPK1KDM4E | |
| SCHEMBL17570604 | 0.68 | ELANE (0.39) | MAOAMAOBHTTCYP19A1ACHE | |
| SCHEMBL5475602 | 0.68 | MEN1 (0.42) | MEN1KMT2AMAPK1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |