Phosphoric Acid

Phosphoric Acid

SCHEMBL16701258

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.[Fe]

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
SLC34A1 Q06495 1/20 0.46
FDPS P14324 2/20 0.42
BLM P54132 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MMP2 P08253 1/20 0.42
THRB P10828 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TYMS P04818 1/20 0.36
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL544314 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL28131561 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL8100898 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL33552 1.00
Phosphoric Acid SCHEMBL15400931 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL28366621 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL28363152 1.00 CA2 (0.50) CA2SLC34A1FDPSBLMTDP1
Phosphoric Acid SCHEMBL1777622 1.00
Phosphoric Acid SCHEMBL25279435 0.94
Phosphoric Acid SCHEMBL400037 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109809382-B Method for synthesizing iron phosphate by using waste phosphate generated by precipitating trace heavy metals 衢州华友钴新材料有限公司 2020-12-11 CN disclosed
US-20200360428-A1 Methods of Reducing Doses of Erythropoietin Stimulating Agents in Hyporesponsive Patients ROCKWELL MEDICAL INC (US) 2020-11-19 US disclosed
CN-108039491-B Sodium iron triphosphate as cathode material of sodium ion battery and preparation method thereof 华南理工大学 2020-05-22 CN disclosed
EP-3065762-A1 METHODS OF REDUCING DOSES OF ERYTHROPOIETIN STIMULATING AGENTS IN HYPORESPONSIVE PATIENTS Rockwell Medical Inc. (US) 2016-09-14 EP disclosed
US-20160250254-A1 METHODS OF REDUCING DOSES OF ERYTHROPOIETIN STIMULATING AGENTS IN HYPORESPONSIVE PATIENTS INNOVATUS LIFE SCIENCES LENDING FUND I, LP 2016-09-01 US disclosed
WO-2015069656-A8 METHODS OF REDUCING DOSES OF ERYTHROPOIETIN STIMULATING AGENTS IN HYPORESPONSIVE PATIENTS ROCKWELL MEDICAL, INC. (US) 2016-05-19 WO disclosed
WO-2015069656-A1 METHODS OF REDUCING DOSES OF ERYTHROPOIETIN STIMULATING AGENTS IN HYPORESPONSIVE PATIENTS ROCKWELL MEDICAL, INC. (US) 2015-05-14 WO disclosed