Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.59 |
| ▸ | BCR | P11274 | 14/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649032 | 0.84 | ABL1 (0.56) | ABL1BCRSMN1; SMN2TSHRLMNA | |
| SCHEMBL30919741 | 0.84 | HCRTR2 (0.47) | ABL1BCRSMN1; SMN2KMT2ATSHR | |
| SCHEMBL17700131 | 0.81 | ABL1 (0.52) | ABL1BCR | |
| SCHEMBL1939014 | 0.79 | ABL1 (0.53) | ABL1BCRTDP1 | |
| SCHEMBL3344468 | 0.78 | ALDH1A1 (0.63) | ABL1BCRTSHR | |
| SCHEMBL4304308 | 0.77 | ABL1 (0.52) | ABL1BCRSMN1; SMN2 | |
| SCHEMBL14276379 | 0.76 | SLC9A1 (0.53) | ABL1BCR | |
| SCHEMBL3537856 | 0.76 | MAPT (0.48) | ABL1BCRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4304306 | 0.74 | ABL1 (0.48) | ABL1BCR | |
| SCHEMBL10491684 | 0.74 | ABL1 (0.45) | ABL1BCRSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069752-A9 | ACETYLCHOLINE BINDING PROTEIN LIGANDS, COOPERATIVE NACHR MODULATORS AND METHODS FOR MAKING AND USING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-09 | — | — | WO | disclosed |
| WO-2015069752-A1 | ACETYLCHOLINE BINDING PROTEIN LIGANDS, COOPERATIVE NACHR MODULATORS AND METHODS FOR MAKING AND USING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-05-14 | — | — | WO | disclosed |