Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265354 | 0.82 | KMT2A (0.42) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL6343043 | 0.81 | SLC6A4 (0.41) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL1068693 | 0.79 | LMNA (0.48) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL11915432 | 0.79 | LMNA (0.48) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL8269660 | 0.79 | LMNA (0.48) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL16400827 | 0.78 | TAAR1 (0.39) | SLC6A4KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2066064 | 0.77 | TAAR1 (0.41) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL2482267 | 0.77 | GSR (0.53) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL20912965 | 0.77 | HTR2C (0.40) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 | |
| SCHEMBL2064318 | 0.77 | GSR (0.53) | SLC6A4SLC6A2KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318558-A2 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | Technion Research & Development Foundation Limited (IL) | 2018-05-09 | — | — | EP | disclosed |
| EP-3066081-B1 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | TECHNION RES & DEV FOUNDATION (IL) | 2018-04-25 | — | — | EP | disclosed |
| US-9637462-B2 | Process for the preparation of N-iodoamides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-05-02 | — | — | US | disclosed |
| US-9637462-B2 | Process for the preparation of N-iodoamides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-05-02 | — | — | US | disclosed |
| US-20160272598-A1 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2016-09-22 | — | — | US | disclosed |
| US-20160272598-A1 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2016-09-22 | — | — | US | disclosed |
| EP-3066081-A2 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | Technion Research & Development Foundation Ltd. (IL) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015068159-A2 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2015-05-14 | — | — | WO | disclosed |
| CN-101421256-A | Thiadiazolidinone inhibitors of ptpase | NOVARTIS AG (CH) | 2009-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272598-A1 | PROCESS FOR THE PREPARATION OF N-IODOAMIDES | INMT, NPM1, B2M | SLC6A4 939/4885SLC6A2 2755/4885KMT2A 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.