Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051817 | 0.88 | POLB (0.50) | LMNATSHRFFAR1NPC1RAB9A | |
| SCHEMBL16703151 | 0.88 | POLB (0.50) | LMNATSHRFFAR1NPC1RAB9A | |
| SCHEMBL17451407 | 0.81 | FFAR1 (0.42) | LMNATSHRFFAR1CYP1A2CYP2D6 | |
| SCHEMBL22610059 | 0.79 | NR4A2 (0.47) | FFAR1NPC1RAB9APOLBFAAH | |
| SCHEMBL4726535 | 0.77 | FFAR1 (0.46) | FFAR1NPC1RAB9AHSP90AA1POLB | |
| SCHEMBL15079869 | 0.73 | MAOB (0.58) | FFAR1CYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL3961295 | 0.70 | FFAR1 (0.59) | LMNAFFAR1PPARGPPARALTA4H | |
| SCHEMBL14967365 | 0.70 | NR4A2 (0.73) | LMNATSHRFFAR1NPC1RAB9A | |
| SCHEMBL14966315 | 0.70 | MAPT (0.68) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL4779408 | 0.69 | FFAR1 (0.48) | FFAR1NPC1RAB9AHSP90AA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015068142-A2 | COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS, USES AND METHOD OF MANAGEMENT OF MYELOPROLIFERATIVE DISORDER | CELLWORKS GROUP, INC. (US) | 2015-05-14 | — | — | WO | disclosed |