Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.45 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726535 | 0.93 | FFAR1 (0.46) | FFAR1NR4A2SIRT2SLC2A1NPC1 | |
| SCHEMBL4725186 | 0.91 | NR4A2 (0.60) | FFAR1NR4A2NPC1RAB9AMAPT | |
| SCHEMBL4725923 | 0.84 | NR4A2 (0.57) | FFAR1NR4A2NPC1RAB9AMAPT | |
| SCHEMBL22610059 | 0.83 | NR4A2 (0.47) | FFAR1NR4A2SIRT2NPC1RAB9A | |
| SCHEMBL27555763 | 0.82 | TDP1 (0.56) | FFAR1NR4A2NPC1RAB9ANR4A1 | |
| SCHEMBL1051817 | 0.80 | POLB (0.50) | FFAR1NR4A2NPC1RAB9AMAPT | |
| SCHEMBL16703151 | 0.80 | POLB (0.50) | FFAR1NR4A2NPC1RAB9AMAPT | |
| SCHEMBL4257586 | 0.80 | AKR1C3 (0.49) | NPC1RAB9APOLB | |
| SCHEMBL4777687 | 0.78 | KMT2A (0.49) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL24401235 | 0.76 | TDP1 (0.60) | FFAR1NPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016278-A1 | FURAN-2-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-02-07 | — | — | WO | disclosed |