Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704020 | 0.84 | NPC1 (0.47) | PARP1SCN9ASCN10APDK2SLC9A1 | |
| SCHEMBL16704113 | 0.83 | PDK2 (0.43) | PARP1SCN9ASCN10APDK2SLC9A1 | |
| SCHEMBL18092820 | 0.76 | STK10 (0.44) | PARP1SCN9ASCN10APDK2SLC9A1 | |
| SCHEMBL16704104 | 0.72 | SCN9A (0.41) | PARP1SCN9ASCN10APDK2SLC9A1 | |
| SCHEMBL6173681 | 0.68 | PARP1 (0.52) | PARP1SCN9ASCN10ACCNCCDK8 | |
| SCHEMBL3347622 | 0.67 | FFAR1 (0.40) | CYP3A4 | |
| SCHEMBL16739633 | 0.67 | CDC7 (0.46) | PARP1SCN9ASCN10ACCNCCDK8 | |
| SCHEMBL30290153 | 0.66 | PARP1 (0.45) | PARP1SCN9ASCN10AMAPK8MAPK10 | |
| SCHEMBL30608075 | 0.66 | PARP1 (0.56) | PARP1SCN9ASCN10APDK2SLC9A1 | |
| SCHEMBL5143960 | 0.66 | PARP1 (0.56) | PARP1SCN9ASCN10APDK2SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065728-A1 | NOVEL METHODS | Aeromics, Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015069948-A1 | NOVEL METHODS | AEROMICS, LLC (US) | 2015-05-14 | — | — | WO | disclosed |